Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men
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منابع مشابه
Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.
Testosterone (T) exerts negative feedback on the hypothalamo-pituitary (GnRH-LH) unit, but the relative roles of the CNS and pituitary are not established. We postulated that relatively greater LH responses to flutamide (brain-permeant antiandrogen) than bicalutamide (brain-impermeant antiandrogen) should reflect greater feedback via CNS than pituitary/peripheral androgen receptor-dependent pat...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2010
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00300.2010